In my case I was deep in an art career, and playing a little on the side with fan fiction. For ten years, no original fiction, not even a sustained longing to attack all my old WIPS. Didn't miss it. Even told my first agent I was probably out of the game.
June 2009, I woke up from an H1N1 fever-dream knowing exactly how to finish a scene on a book stalled ten years previous. And then I didn't stop.
I find very dark chocolate works wonders.
I tried to keep writing after my third child was born, but there just were not enough hours in the day -- or energy in my body -- to be a full time writer and a mother, too. So I stopped when Third Child was about six months old, and left off until about 2004, which is ten years almost exactly.
I got started back because of the SCA. We had a woman in our shire whom I adored, and whom we all loved teasing (not hurtful; if we failed to tease her at least a little, she would complain that we were ignoring her! LOL). One day I wrote a WANTED poster about her, and tacked it up where everybody could see it; the wanted poster had a list of silly "crimes" she had committed, a bunch of Viking jokes, and lots of alliteration. Everybody loved it so much (the woman? She demanded copies!).
It felt so good to have that kind of affirmation for such a little thing, I ended up writing a short story about the lady and her best friend. Ended up reading it out loud at feast, and brought the house down; the king even kissed me and said he hadn't laughed so hard in years.
From there, it kind of snowballed. Everybody wanted a story. I ended up writing a whole cycle of stories about the various members of our local SCA community. Culminated when the Aethelmearc King read out one of my stories at a party to commemorate the elevation of one of our group (naturally the story was about that person being elevated).
After that, I was off and running. There are times (like every time I sit down to write) that I wish I'd kept writing through that ten year time; maybe I'd be more successful now. But I can't take that time back and I don't really want to, not truly. There was not enough me to go around to both writing and my enormous family, and I had to choose. I didn't make the wrong choice, not for me; your mileage may vary.