I'm really interested to see where this goes in season 2. Spader is brilliant and they get some good actors to play the blacklisters of the week, but the supporting cast... well, maybe if Red tells me Lizzy is special fifty more times, I'll start to believe him. (Liked her in the pilot, by the way.)
I hope the plotting gets stronger. There were times last season when they were kicking their wheels and there was a key mistake in the pilot that nearly messed up the entire season for me. When Red (who is basically always right) tells Lizzy not to trust her husband, I believe him. So then I spent episode after episode waiting for Lizzy's marriage to finally crumble so we could get to the obvious reveal.
This show still has major potential though. I'm just concerned that it could collapse under the weight of its own vague back story since it's basically being carried solely by the awesomeness that is James Spader as Red.